D-Mannose

D-mannose is a simple sugar that is found in many fruits and is related to glucose. D-mannose also occurs naturally in some cells of the human body. Other names for D-mannose are carubinose, D-mannosa, mannose and seminose

What is D-mannose used for?

D-mannose is used to treat a rare disease called Carbohydrate-Deficient Glycoprotei Syndrome Type 1b.

This disease is inherited and results in protein being lost through the digestive tract. Some reports suggest that D-mannose slows down this protein loss and allows the liver to function better. D-Mannose may also reduce bleeding disorders and lower blood sugar in people suffering from this disease. In addition, D-mannose could treat or prevent urinary tract infections. Studies carried out on animals suggest that this supplement prevents certain bacteria from adhering to the walls of the bladder. Scientists suspect that these bacteria attach themselves to this sugar instead. This helps to eliminate these bacteria from the body via the urine. Fewer bacteria in the bladder reduce the risk of urinary tract infections. However, no human studies have been conducted to determine whether D-mannose is effective in treating or preventing urinary tract infections. Some studies suggest that D-mannose may play a role as a beneficial prebiotic. Prebiotics are substances that help the body to stimulate the growth of beneficial bacteria in the digestive tract. Studies conducted with mice have shown that D-mannose components promote the growth of beneficial bacteria. This suggests that D-mannose may be beneficial for people suffering from an imbalance of beneficial and harmful bacteria.

D-Mannose supplements are taken orally.

Can D-Mannose be taken naturally through food?

D-mannose is found in high concentrations in many fruits. Such fruits include apples, oranges, peaches and some berries such as blueberries and cranberries

Risks and side effects

Long-term studies in mice suggest that oral intake of D-mannose in adequate amounts is safe and harmless. Pregnant or breastfeeding women should be cautious when using D-Mannose as there is insufficient research on the safety of D-Mannose in pregnant or breastfeeding women. Side effects of D-Mannose may include bloating and loose stools. D-Mannose should be used with caution by diabetics as it can make blood sugar control more difficult. High amounts of D-Mannose can cause kidney damage.