Catechu
Catechu, also known as “Khair” or “Katha”, is a plant extract obtained from the wood and bark of Acacia catechu. The plant is native to South Asia and has been used for centuries in Ayurvedic and traditional Chinese medicine. Catechu is known for its astringent, anti-inflammatory, and antioxidant properties. In traditional medicine, it is used in the treatment of mouth and throat infections and digestive complaints, as well as a natural dental care ingredient.
What benefits does Catechu offer?
Although the traditional use of Catechu is widespread, there are only limited scientific studies that substantiate its effects. Traditionally, various parts of the plant are used, for example, for colds, in the context of dental health, for digestive and skin problems, rheumatism, and other complaints (1,2,3,4). While scientific studies on the plant should be viewed critically, so far they suggest, among other things, the following potential health benefits:
- Immunomodulatory effects: Studies suggest that Catechu could be used as an immunomodulatory agent (1,5)
- Effect on blood glucose levels: In studies, extracts of the plant were able to have a positive effect on blood sugar levels (1,6,7,8)
- Antihyperlipidemic activity: In studies, extracts from the root improved serum HDL levels and effectively lowered serum triglyceride levels, total cholesterol, VLDL, and LDL (1,9)
- Antioxidant effects: Catechu contains high amounts of polyphenols, which can fight free radicals in the body (1,10,11).
- Antiproliferative effects: Studies have associated Catechu with an antiproliferative effect, meaning an effect that can inhibit tissue proliferation (12,13).
- Antimicrobial effects: In studies, extracts of the plant showed an inhibitory effect on both bacteria and fungal species (1,14,15)
Although these benefits are promising, further clinical studies are necessary to better understand the exact mechanisms of action and the safety of Catechu. Moreover, results from studies are often not readily transferable.
How does Catechu work?
The health properties of Catechu are attributed primarily to the polyphenols and tannins it contains. These bioactive compounds can exert various effects in the body.
Dosage recommendation
The dosage of Catechu depends on the form of use. It is available as a powder, extract, or in processed form (e.g., in dental care products). In Ayurvedic medicine, Catechu is often used as a tea or in small amounts as an ingredient in herbal blends. Since high doses can cause stomach irritation, Catechu should only be taken in moderate amounts and ideally after consulting a doctor.
Can Catechu be obtained naturally through food?
In some regions, Catechu is used as a spice or additive in beverages. Especially in India, it is a common ingredient in certain herbal preparations and is occasionally consumed with betel leaves. However, excessive consumption should be avoided, as Catechu has astringent properties and can lead to stomach complaints at high doses.
What risks does the use of Catechu involve?
- Side effects: With excessive intake, Catechu can cause stomach irritation, constipation, or nausea.
- Risks: Pregnant and breastfeeding women as well as people with a sensitive stomach should use Catechu with caution.
- Interactions: Catechu could influence the absorption of certain medications, especially those that regulate stomach acid production. People who take medications regularly should consult a doctor before use.
Conclusion
Catechu is a traditional herbal remedy with potential health benefits for various aspects of health. Thanks to its versatile properties, it is used in numerous natural remedies. Nevertheless, it should be consumed in moderation, as high doses can cause stomach irritation. Further scientific studies are required to comprehensively confirm the long-term safety and efficacy of Catechu.
Sources:
- Kumari M, Radha, Kumar M, Zhang B, Amarowicz R, Puri S, Pundir A, Rathour S, Kumari N, Chandran D, Dey A, Sharma N, Rajalingam S, Mohankumar P, Sandhu S, Pant N, Ravichandran RP, Subramani M, Pandi K, Muthukumar M, Zengin G, Mekhemar M, Lorenzo JM. Acacia catechu (L.f.) Willd.: A Review on Bioactive Compounds and Their Health Promoting Functionalities. Plants (Basel). 2022 Nov 14;11(22):3091. doi: 10.3390/plants11223091. PMID: 36432824; PMCID: PMC9697042.
- Joshi A.R., Joshi K. Indigenous knowledge and uses of medicinal plants by local communities of the Kali Gandaki Watershed Area, Nepal. J. Ethnopharmacol. 2000;73:175–183. doi: 10.1016/S0378-8741(00)00301-9.
- Singh A.G., Kumar A., Tewari D.D. An ethnobotanical survey of medicinal plants used in Terai forest of western Nepal. J. Ethnobiol. Ethnomed. 2012;8:1–15. doi: 10.1186/1746-4269-8-19.
- Samant S.S., Vidyarthi S., Pant S., Sharma P., Marpa S., Sharma P. Diversity, distribution, indigenous uses and conservation of the medicinal plants of Indian Himalayan region used in cancer. J. Biodivers. 2011;2:117–125. doi: 10.1080/09766901.2011.11884732.
- Ismail S., Asad M. Immunomodulatory activity of Acacia catechu. Indian J. Physiol. Pharmacol. 2009;53:25–33.
- Aryal B., Adhikari B., Aryal N., Bhattarai B.R., Khadayat K., Parajuli N. LC-HRMS Profiling and Antidiabetic, Antioxidant, and Antibacterial Activities of Acacia catechu (Lf) Willd. Biomed Res. Int. 2021;2021:1–16. doi: 10.1155/2021/7588711.
- Lakshmi T., Ramasamy R., Thirumalaikumaran R. Preliminary Phytochemical analysis and In vitro Antioxidant, FTIR Spectroscopy, Anti-diabetic activity of Acacia catechu ethanolic seed extract. Pharmacogn. J. 2015;7:356–362. doi: 10.5530/pj.2015.6.7.
- Ray D., Sharatchandra K.H., Thokchom I.S. Antipyretic, antidiarrhoeal, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu Willd. in albino rats. Indian J. Pharmacol. 2006;38:408–413. doi: 10.4103/0253-7613.28207.
- Arise R.O., Akapa T., Adigun M.A., Yekeen A.A., Oguntibeju O.O. Normoglycaemic, normolipidaemic and antioxidant effects of ethanolic extract of Acacia ataxacantha root in streptozotocin-induced diabetic rats. Not. Sci Biol. 2016;8:144–450. doi: 10.15835/nsb829770.
- Kumar R., Mahey S., Arora R., Mahajan J., Kumar V., Arora S. Insights into biological properties of less explored bark of industrially important Acacia catechu Willd. Ind. Crops Prod. 2019;138:111486. doi: 10.1016/j.indcrop.2019.111486.
- Aryal B., Adhikari B., Aryal N., Bhattarai B.R., Khadayat K., Parajuli N. LC-HRMS Profiling and Antidiabetic, Antioxidant, and Antibacterial Activities of Acacia catechu (Lf) Willd. Biomed Res. Int. 2021;2021:1–16. doi: 10.1155/2021/7588711.
- Lakshmi T., Ezhilarasan D., Nagaich U., Vijayaragavan R. Acacia catechu ethanolic seed extract triggers apoptosis of SCC-25 cells. Pharmacogn. Mag. 2017;13:405–411. doi: 10.4103/pm.pm_458_16.
- Isemura M. Catechin in human health and disease. Molecules. 2019;24:528. doi: 10.3390/molecules24030528.
- Joshi S., Subedi Y.P., Paudel S.K. Antibacterial and antifungal activity of heartwood of Acacia catechu of Nepal. J. Nepal Chem. Soc. 2011;27:94–99. doi: 10.3126/jncs.v27i1.6667.
- Patel J.D., Kumar V., Bhatt S.A. Antimicrobial screening and phytochemical analysis of the resin part of Acacia catechu. Pharm. Biol. 2009;47:34–37. doi: 10.1080/13880200802400527.