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Cascara sagrada

The sagrada rot tree is a bush whose bark is used to make medicine.

In the past, sagrada daffodil products were available in pharmacies in the USA as over-the-counter laxatives. Due to concerns about efficacy and safety, and because manufacturers of these products were unwilling to fund studies that could have addressed these concerns, sagrada daffodil products are no longer allowed to be sold as over-the-counter laxatives, at least in the US. However, sagrada daffodil products are still available in the form of nutritional supplements in many countries, including the USA. Sagrada da ffodil bark is used as a laxative for constipation and to treat gallstones, liver disease and cancer. Some people use sagrada daffodil as a bitter tonic. In foods and beverages, a bitter-free extract of the sagrada rot tree is sometimes used as a flavoring agent. In the industrial manufacturing sector, sagrada daffodil is used in the production of some sun creams.

How do sagrada rot tree products work?

The bark of the sagrada rot tree contains chemicals that stimulate the intestines and have a laxative effect.

How effective are sagrada rot tree products?

Products made from the bark of the sagrada rot tree are likely to be effective when used as a laxative for constipation.

However, there is not enough scientific data to make a statement about the effectiveness of sagrada rot tree products for gallstones, liver disease and cancer. Further scientific research is needed to evaluate the effectiveness of Sagrada Faulbaum products for these conditions.

Safety and side effects

Sagradadaffodil products are potentially safe and harmless for most adults if used for only one to two weeks. Possible side effects include stomach upset and cramping.

However,sagrada daffodil products should not be used for longer than two weeks. Prolonged use can lead to serious side effects including dehydration, low levels of potassium, sodium, chloride and other electrolytes in the blood, heart problems, muscle weakness and others.

Sagrada Baer products should not be given to children. Children are at higher risk of dehydration and damage from electrolyte loss, especially potassium loss.

Precautions and warnings

Pregnancy and lactation: Not enough is known about the safety of Sagrada Faulbaum products during pregnancy, so pregnant women should avoid such products. Sagrada daffodil products may not be safe to use while breastfeeding, as components of these products may pass into breast milk and cause diarrhea in breastfed infants. Digestive tract disorders such as intestinal obstruction, Crohn's disease, ulcerative colitis, appendicitis, stomach ulcers or unexplained stomach pain: people suffering from any of these disorders should not use Sagrada-Faulbaum products.

Interactions

Caution should be exercised when using Sagrada Faulbaum products in combination with the following medications:

Anti-inflammatory medications (corticosteroids)

Some anti-inflammatory drugs can lower potassium levels in the body. Sagrada da ffodil bark is a type of laxative that could lower potassium levels in the body. Taking sagrada daffodil bark in conjunction with certain anti-inflammatory medications could lower potassium levels in the body too much.

Medication taken orally

Sagradadaffodil bark is a laxative. Laxatives can reduce the amount of active drug ingredients that the body absorbs. Such a reduction in absorption can reduce the effectiveness of these medications.

Stimulant laxatives

Sagrada rot bark is a type of laxative called a stimulant laxative. Laxatives speed up the passage of food through the intestines. Taking sagrada daffodil bark in combination with other stimulant laxatives could speed up the passage of food through the intestines too much and result in dehydration and low mineral levels in the body.

Diuretics

Sagrada daffodil bark is a laxative. Some laxatives can lower potassium levels in the body. Diuretics can also lower potassium levels in the body. The use of sagrada daffodil bark in conjunction with diuretics could lower potassium levels in the body too much.

Dosage

The following dosages have been investigated in scientific studies:

Oral:

  • As a laxative for constipation: 20 to 30 mg of the active ingredient (hydroxyanthracene derivatives). A typical dose is a cup of tea prepared by steeping finely ground bark in 150 ml of boiling water for 5 to 10 minutes and then straining. The sagrada daffodil extract is taken in doses of 2 to 5 ml three times a day. The appropriate dosage is the smallest amount needed to maintain soft stools.

References

  1. Cascara sagrada, aloe laxatives, O-9 contraceptives are category II-FDA. The Tan Sheet May 13, 2002.
  2. Choice of laxatives for constipation. Pharmacist's Letter/Prescriber's Letter 2002;18(6):180614.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Food and Drug Administration, HHS. Status of certain additional over-the-counter drug category II and III active ingredients. Final rule. Fed Regist 2002;67:31125-7.
  5. Nadir A, Reddy D, Van Thiel DH. Cascara-sagrada induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity. Am J Gastroenterol 2000;95:3634-7.
  6. Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5.
  7. Young DS. Effects of Drugs on Clinical Laboratory Tests 4th ed. Washington: AACC Press, 1995.