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Citrus Bergamot · 90 capsules

by GN Laboratories
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€29,90
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Citrus Bergamot is an active ingredient that has become increasingly popular among strength athletes in recent years. It is said to improve cholesterol and blood lipid levels (1), inhibit inflammation (2) and protect cardiovascular health via multiple pathways (3).

  • Has a whole range of positive effects
  • Influences cholesterol and blood lipid levels (1)
  • Anti-inflammatory properties (2)
  • Easy to dose capsule form
  • Highest quality - Made in Germany
Nährwerte und Inhaltsstoffe
Compositionper capsule
Citrus Bergamot500 mg
of which 35% polyphenols175 mg


Zutaten: Citrus bergamot extract (35% polyphenols), anti-caking agent: rice bran extract, capsule shell: hydroxypropyl methylcellulose.

*Prozent der empfohlenen täglichen Verzehrmenge laut Verordnung (EU) Nr. 1196/2011

**Keine Nährstoffbezugswerte (NRV) vorhanden.

Verzehrempfehlung

Take 1-3 capsules a day with plenty of liquid.

Hinweise

Hersteller / Distributor

GN Laboratories Europe, London / United Kingdom

Nero Labs BV, Postbus 278, 5900AG Venlo, The Netherlands

Quellen
  1. Nauman MC, Johnson JJ. Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integr Food Nutr Metab. 2019 Mar;6(2):10.15761/IFNM.1000249. doi: 10.15761/IFNM.1000249. Epub 2019 Feb 28. PMID: 31057945; PMCID: PMC6497409.
  2. Ferlazzo N, Cirmi S, Calapai G, Ventura-Spagnolo E, Gangemi S, Navarra M. Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand? Molecules. 2016 Sep 23;21(10):1273. doi: 10.3390/molecules21101273. PMID: 27669206; PMCID: PMC6274179
  3. Toth PP, Patti AM, Nikolic D, Giglio RV, Castellino G, Biancucci T, Geraci F, David S, Montalto G, Rizvi A, Rizzo M. Bergamot Reduces Plasma Lipids, Atherogenic Small Dense LDL, and Subclinical Atherosclerosis in Subjects with Moderate Hypercholesterolemia: A 6 Months Prospective Study. Front Pharmacol. 2016 Jan 6;6:299. doi: 10.3389/fphar.2015.00299. PMID: 26779019; PMCID: PMC4702027.
  4. Da Pozzo E, De Leo M, Faraone I, Milella L, Cavallini C, Piragine E, Testai L, Calderone V, Pistelli L, Braca A, Martini C. Antioxidant and Antisenescence Effects of Bergamot Juice. Oxid Med Cell Longev. 2018 Jul 12;2018:9395804. doi: 10.1155/2018/9395804. PMID: 30116497; PMCID: PMC6079356.
  5. Cappello AR, Dolce V, Iacopetta D, Martello M, Fiorillo M, Curcio R, Muto L, Dhanyalayam D. Bergamot (Citrus bergamia Risso) Flavonoids and Their Potential Benefits in Human Hyperlipidemia and Atherosclerosis: an Overview. Mini Rev Med Chem. 2016;16(8):619-29. doi: 10.2174/1389557515666150709110222. PMID: 26156545.
  6. Schoeneck M, Iggman D. The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2021 Elzbieta Janda, Antonella Lascala, Concetta Martino, Salvatore Ragusa, Saverio Nucera, Ross Walker, Santo Gratteri, Vincenzo Mollace,
  7. Molecular mechanisms of lipid- and glucose-lowering activities of bergamot flavonoids, PharmaNutrition, Volume 4, Supplement, 2016, Pages S8-S18, ISSN 2213-4344,May 6;31(5):1325-1338. doi: 10.1016/j.numecd.2020.12.032. Epub 2021 Jan 16. PMID: 33762150.
  8. Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ. Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells. Nutrients. 2021 Sep 10;13(9):3156. doi: 10.3390/nu13093156. PMID: 34579033; PMCID: PMC8469228.
  9. Lamiquiz-Moneo I, Giné-González J, Alisente S, Bea AM, Pérez-Calahorra S, Marco-Benedí V, Baila-Rueda L, Jarauta E, Cenarro A, Civeira F, Mateo-Gallego R. Effect of bergamot on lipid profile in humans: A systematic review. Crit Rev Food Sci Nutr. 2020;60(18):3133-3143. doi: 10.1080/10408398.2019.1677554. Epub 2019 Oct 31. PMID: 31670973.
  10. Perna S, Spadaccini D, Botteri L, Girometta C, Riva A, Allegrini P, Petrangolini G, Infantino V, Rondanelli M. Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations. Food Sci Nutr. 2019 Jan 25;7(2):369-384. doi: 10.1002/fsn3.903. PMID: 30847114; PMCID: PMC6392855
  11. Ritchie AI, Wedzicha JA. Definition, Causes, Pathogenesis, and Consequences of Chronic Obstructive Pulmonary Disease Exacerbations. Clin Chest Med. 2020 Sep;41(3):421-438. doi: 10.1016/j.ccm.2020.06.007. PMID: 32800196; PMCID: PMC7423341
  12. de Cássia da Silveira E Sá R, Lima TC, da Nóbrega FR, de Brito AEM, de Sousa DP. Analgesic-Like Activity of Essential Oil Constituents: An Update. Int J Mol Sci. 2017 Dec 9;18(12):2392. doi: 10.3390/ijms18122392. PMID: 29232831; PMCID: PMC5751100
  13. Lombardo GE, Cirmi S, Musumeci L, Pergolizzi S, Maugeri A, Russo C, Mannucci C, Calapai G, Navarra M. Mechanisms Underlying the Anti-Inflammatory Activity of Bergamot Essential Oil and Its Antinociceptive Effects. Plants (Basel). 2020 Jun 1;9(6):704. doi: 10.3390/plants9060704. PMID: 32492797; PMCID: PMC7356015.
  14. Bartella L, Mazzotti F, Talarico IR, De Luca G, Santoro I, Prejanò M, Riccioni C, Marino T, Di Donna L. Structural Characterization of Peripolin and Study of Antioxidant Activity of HMG Flavonoids from Bergamot Fruit. Antioxidants (Basel). 2022 Sep 20;11(10):1847. doi: 10.3390/antiox11101847. PMID: 36290571; PMCID: PMC9598738
  15. Mare R, Mazza E, Ferro Y, Gliozzi M, Nucera S, Paone S, Aversa I, Pujia R, Marafioti G, Musolino V, Mollace V, Montalcini T, Pujia A. A new breakfast brioche containing bergamot fiber prevents insulin and glucose increase in healthy volunteers: a pilot study. Minerva Endocrinol (Torino). 2021 Jun;46(2):214-225. doi: 10.23736/S2724-6507.20.03243-5. Epub 2020 Sep 24. PMID: 32969628.

Inhalt: 90 capsules Artikelnr.: 7642

What is citrus bergamot?

Bergamot is a citrus plant that originated as a cross between the bitter orange and other citrus plants and was first described in the 17th century. Since then, bergamot has been cultivated in Italy, mainly on the coast of Calabria. The extracts obtained from the plant give Earl Grey tea its characteristic aroma and the essential oils of bergamot are used in perfume production and aromatherapy. What was not known for a long time is that bergamot is very rich in polyphenols. Like the essential oils of bergamot, these have a variety of health benefits and, according to studies, also have pronounced antioxidant properties (4).

How can citrus bergamot improve cardiovascular health?

Citrusbergamot is an active ingredient that has been shown to improve cholesterol and blood lipid levels in study subjects. Elevated levels in these areas are two of the primary risk factors for cardiovascular disease (5). These risk factors are becoming increasingly important in today's world and affect not only people who do not exercise enough, but also athletes who have unhealthy eating habits (6). High levels of harmful LDL cholesterol promote deposits in the blood vessels, which can lead to constrictions or blockages and are therefore the primary trigger for a heart attack. Healthy HDL cholesterol counteracts such deposits by promoting the removal of LDL cholesterol. Scientific studies have shown that citrus bergamot was able to significantly reduce harmful LDL cholesterol levels. At the same time, it was able to significantly increase healthy HDL cholesterol levels (1,3, 8). In addition, a significant reduction in blood triglyceride levels was also observed. In contrast to statins, which are used in the medical field as cholesterol-lowering agents, citrus bergamot does not inhibit the body's own production of coenzyme Q10 (9). Another benefit that has been associated with the use of citrus bergamot in studies is its antioxidant properties, which can counteract the oxidation of LDL cholesterol (4). This is of particular interest as oxidized LDL cholesterol can contribute significantly more than intact LDL cholesterol to plaque formation in the blood vessels (i.e. calcification of the arteries) (1,3).

Other effects of citrus bergamot proven in studies

Citrusbergamot has been associated with helping to keep blood vessels healthy (10). Chronic systemic inflammation is common and is associated with an increased risk of many diseases, including cardiovascular disease (11). Particularly critical in this regard is the inner lining of the veins known as the endothelium, which is directly involved in vasodilation, blood pressure regulation, blood clotting and many other important processes. Citrus bergamot has been shown to reduce inflammation and plaque formation and improve the elasticity and responsiveness of the veins in test subjects. This is partly due to its pronounced anti-inflammatory properties, which are achieved by reducing the levels of pro-inflammatory cytokines (3, 12, 13). In addition, citrus bergamot has been shown to protect the cells of the endothelium from free radical damage through its antioxidant properties, which could also promote the health of the endothelium and consequently that of the blood vessels (4, 14). Another effect of bergamot is related to insulin sensitivity. Scientific studies have shown that citrus bergamot can improve insulin sensitivity by activating AMPK, resulting in a significant reduction in blood glucose levels (10,15).

CitrusBergamot is a supplement that has been shown to have numerous positive effects on subjects in various studies. It is therefore hardly surprising that the active ingredient is also becoming increasingly popular in Germany. As always, the effect of the supplement stands and falls with the quality of the ingredients. As usual, GN relies exclusively on raw materials of the best quality in order to always be able to guarantee an optimum effect. **Citrus Bergamot from GN Laboratories - because in the end only results count.

Customer Reviews

Based on 9 reviews
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M
Manuel H.
Quellenangaben

Schön, dass man hier Quellenangaben zu den Aussagen bekommt die getroffen werden

M
Marcel Sunderbach
Solide das Gigas auch das hier hat.

Leider immernoch ein seltener Wirkstoff, Gigas enttäuscht hier aber nicht

M
Manni D.
Citrus Bergamot

Wichtig wenn man seine Gesundheit unter besonderen Umständen so gut es geht erhalten möchte.

P
Paul Ungerer
Klasse Wirkung

Absolut geiles Produkt, nur leider auf der teureren Seite. Was soll ich sagen bin froh dass es hier überhaupt in dieser Form und Qualität erhältlich ist

K
Korbinian G.
Sehr zufrieden

Echt ein tolles Produkt, dass ich nur jedem empfehlen kann der davon profitieren könnte 😉

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