Nano Pure Beta Alanine · 500g

Benefits of beta alanine?

Betaalanine is probably one of the most promising active ingredients since the market launch of creatine almost 30 years ago, at least if the results of numerous studies are to be believed. Researchers have been able to prove that beta alanine has performance-enhancing and muscle-building effects. These effects have been proven by a large number of human studies carried out on trained athletes rather than rats or non-athletic people. Beta alanine enabled the test subjects to perform harder and more intensive training sessions with weights (1), as well as a significant increase in performance in endurance sports. Supplementation with beta alanine significantly delayed the onset of muscle fat igue (2). But the benefits that beta alanine has shown in studies do not end there. It was able to improve the muscle build-up of the test subjects (3), accelerate regeneration after training (4) and even increase the pump during training (5).

How does beta alanine work?

Betaalanine is a non-proteinogenic amino acid that occurs naturally in food - and primarily in animal foods. In the human body, beta alanine is one of the two starting substances from which the body's strongest intramuscular acid blocker is produced. This is known as carnosine and is of great importance for a number of processes in the human body. Beta-alanine is considered the limiting factor in carnosine production. It therefore limits the rate of carnosine production. In conclusion, this means that the more beta-alanine the body has available, the more carnosine it produces (6). Studies have shown that carnosine levels in muscle tissue increased dramatically by 65% within 4 weeks when supplemented with 3 grams of beta alanine per day, and an increase of 80% was possible with further supplementation (7, 8).

Benefits of carnosine for strength and endurance athletes?

During intense muscular exertion, large amounts of hydrogen atoms are inevitably released both as part of the energy release from ATP and as part of the energy production from glucose known as glycolysis. These lower the pH value within the muscles and can thus lead to hyperacidity of the muscles (9). This acidosis manifests itself, among other things, in the specific muscle burn at the end of a set that every hard-training athlete is familiar with. Unfortunately, like any other body tissue, muscles only function optimally within a narrow pH range. This in turn means that hyperacidity can severely restrict the function of many processes within the muscles that are important for performance, regeneration and muscle building (10). This is exactly where carnosine comes into play. Carnosine neutralizes the excess amounts of hydrogen ions and can therefore effectively counteract acidification of the muscles. The more carnosine is stored in the muscles, the longer muscle acidification can be delayed (4). Beta alanine therefore indirectly ensures a later onset of hyperacidity and thus leads to the benefits proven in studies.

How can beta alanine increase training performance?

Acidification of the muscles based on an increase in hydrogen ions led to a reduction in strength in test subjects in one study and to a faster onset of muscle fatigue (11). The contractility of the muscle fibers decreases rapidly with increasing acidification until finally a state of muscle failure occurs. In turn, this means that a reduction in this acidification by carnosine means that theoretically more intensive repetitions can be performed per heavy training set. This effect was also observed in test subjects in a study (2). It is known that a higher potential volume can also provide a stronger stimulus for growth (12). At the same time, neutralization of the acid accelerates recovery between training sets and enabled the test group in one study to perform more hard training sets per training session (13). Beta alanine also had a beneficial effect on the pump during training. Scientific studies have come to the conclusion that carnosine is the primary substrate from which the body produces the enzyme nitric oxide synthase (1). This in turn is required for the production of nitric oxide from arginine and citrulline. In other words, this means that the increased carnosine levels resulting from beta alanine supplementation can significantly increase muscle pumps during training (14). But that's not all. The arginine - nitric oxide synthase - nitric oxide pathway, which the body primarily uses to produce nitric oxide, becomes increasingly inefficient as muscle acidity increases. As carnosine is a very effective acid blocker, it can therefore keep nitric oxide production via this pathway in the maximum range for longer during training and thus increase the "pump effect" (3). Beta alanine has also been shown to have a more direct effect on protein synthesis and protein degradation in subjects in scientific studies (15). This effect is also related to acidification of the muscles. Scientific studies have come to the conclusion that an acidic environment in the muscles inhibits the uptake of amino acids into the muscle cells, the activation of the mTOR pathway and thus ultimately also protein synthesis (4). This means that training-induced muscle acidosis results in more muscle breakdown during and after training. But it also means that it takes significantly longer for the body to start repairing muscle tissue damaged during exercise and building new muscle tissue(16). The good news is that by reducing muscle acidity, carnosine can help minimize the negative effects of acidosis by both reducing muscle breakdown and leading to afaster transition from an exercise-induced catabolic, muscle-degrading environment to an anabolic, muscle-building environment (17).

Tips for optimal use of beta alanine

Since beta alanine increases carnosine levels over time, a daily intake of 3 grams of beta alanine, the amount used in clinical studies, is recommended. In order to achieve the fastest possible increase in carnosine concentration, up to 5 grams of beta alanine can be taken during the first four weeks (18). According to studies, taking carnosine with carbohydrates can accelerate the onset of action, as the insulin release caused by the carbohydrates can increase carnosine absorption. Furthermore, taking it after training can also improve absorption due to the increased amino acid uptake capacity of the muscle cells. Some interesting studies have also shown that a combined intake of creatine and beta alanine has a stronger positive overall effect on aerobic AND anaerobic training performance and muscle building than the purely additive effects of the individual active ingredients due to synergistic mechanisms (12,19).

Is beta alanine safe and what is this tingling sensation on the skin at the beginning of the intake?

In none of the numerous human clinical studies conducted with beta alanine - which lasted up to 12 weeks or longer - were any harmful side effects of beta alanine observed. The only noticeable side effect that can be observed in some users is a slight tingling sensation on the skin after ingestion during the first few days of use. This tingling is due to a completely harmless stimulation of the nerve cells by beta alanine. This initial tingling sensation only occurs immediately after ingestion and disappears again after a short time and can usually be completely avoided by taking beta alanine in combination with carbohydrates or by using several small single doses of less than 1 gram of beta alanine per dose.

Pure quality through NanoPure®

NanoPure® is not just a manufacturer of various dietary supplements or ingredients, NanoPure® stands for the highest quality and maximum purity. All products with the NanoPure® seal of approval are subjected to the strictest testing procedures before they are released for sale. Independent laboratories test every single batch to the highest scientific standards to ensure that no impurities can affect the quality of the products. Anyone who reads NanoPure® on a product can be sure that there are no heavy metals, no extenders and no harmful substances in their product. NanoPure® stands for pure quality.

All in all, the findings that have been collected from test subjects in numerous studies on the use of beta alanine speak for themselves. The amino acid provided the test subjects with numerous benefits for their training and showed significant effects in terms of both regeneration and muscle building. GN Laboratories supplies beta alanine in its purest form - because in the end, only results count.