Berberine · 120 Kapseln
Berberin steht im Ruf, zahlreiche positive Effekte auf den Körper haben zu können. Viele dieser Effekte wurden im Rahmen wissenschaftlicher Studien untersucht und konnten bei verschiedenen Testgruppen nachgewiesen werden.
- Zahlreiche Effekte
- Wissenschaftlich belegt
- Hoch dosiert
- 300 mg Berberin pro Kapsel
- Leicht dosierbare Kapselform
- Bewährte Qualität – Hergestellt in Deutschland
Nährwerte und Inhaltsstoffe
Nährwerttabelle | pro Kapsel |
---|---|
Berberitzen-Extrakt - davon Berberin | 309 mg 300 mg |
Zutaten: Berberitzen-Wurzelextrakt (97% Berberin), Kapselhülle: Hydroxypropylmethylcellulose (pflanzliche Kapselhülle).
*Prozent der empfohlenen täglichen Verzehrmenge laut Verordnung (EU) Nr. 1196/2011
**Keine Nährstoffbezugswerte (NRV) vorhanden.
Verzehrempfehlung
Täglich 1 Kapsel unzerkaut mit ausreichenden Wasser einnehmen.
Hinweise
Die angegebene empfohlene tägliche Verzehrsmenge darf nicht überschritten werden. Nahrungsergänzungsmittel sollten nicht als Ersatz für eine ausgewogene und abwechslungsreiche Ernährung verwendet werden. Das Produkt ist außerhalb der Reichweite von kleinen Kindern zu lagern.
Quellen
- Kulkarni, S. K., & Dhir, A. (2010). Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders. Phytotherapy Research, 24(3), 317-324.
- Yin, J., Xing, H., Ye, J., & Efficacy, S. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism, 57(5), 712-717.
- Kong, W. J., Wei, J., Abidi, P., Lin, M. H., Inaba, S., Li, C., ... & Li, Y. C. (2004). Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature medicine, 10(12), 1344-1351.
- Zhang, Y., Li, X. J., Yan, F. F., & Sun, H. R. (2010). The effects of berberine on hepatic LDLR mRNA and protein expression in rats with non-alcoholic fatty liver disease. Pharmaceutical biology, 48(3), 315-321.
- Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., ... & Ning, G. (2008). Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. The Journal of Clinical Endocrinology & Metabolism, 93(7), 2559-2565.
- Dong, H., Wang, N., Zhao, L., & Lu, F. (2012). Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine, 2012.
- Yin, J., Ye, J., Jia, W., & Efficacy, S. (2008). Effects and mechanisms of berberine in diabetes treatment. Acta Pharmacologica Sinica, 29(10), 1149-1163.
- Wang, Y., & Campbell, T. (2017). Berberine enhances insulin receptor signaling and modifies gene expression of glucose metabolism, inflammation, and mitochondrial biogenesis in culturing human skeletal muscle cells. Evidence-Based Complementary and Alternative Medicine, 2017.
- Kong WJ, Wei J, Zuo ZY, et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med. 2004;10(12):1344-1351. doi:10.1038/nm1135
- Derosa, G., Maffioli, P., & Cicero, A. F. (2015). Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials. Expert Opinion on Biological Therapy, 15(9), 1297-1306.
- Wu, X., Li, Q., Xin, H., Yu, A., Zhong, M., & Guo, X. (2017). Anti-inflammatory and antibacterial activity of berberine in an infected pressure ulcer model. Molecular Medicine Reports, 16(2), 1297-1303.
- Sun, X., & Lv, F. (2015). Berberine: pathway validation and drug discovery. Expert Opinion on Drug Discovery, 10(10), 1033-1044.
- Dong, H., Wang, N., Zhao, L., Lu, F. E., & Xu, L. J. (2012). Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis. Evidence-based complementary and alternative medicine, 2012, 591654. https://doi.org/10.1155/2012/591654
- Hardie, D. G., Ross, F. A., & Hawley, S. A. (2012). AMP-activated protein kinase: a target for drugs both ancient and modern. Chemistry & biology, 19(10), 1222-1236. https://doi.org/10.1016/j.chembiol.2012.08.019
- Wu, L., Xia, M., Duan, Y., Zhang, L., Jiang, H., Hu, X., Yan, H., Zhang, Y., Gu, J., & Xiang, S. (2014). Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. Cell death & disease, 5(2), e1306. https://doi.org/10.1038/cddis.2014.274
- Chang, W., Zhang, M., Li, J., Meng, Z., Wei, S., Du, H., & Zhang, Y. (2013). Berberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase. Metabolism, 62(8), 1159-1167. https://doi.org
- Yin, J., Xing, H., Ye, J., & Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR, 2019. https://doi.org/10.1002/ptr.6549
- Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., Sun, G. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. Journal of Ethnopharmacology, 161, 69-81. https://doi.org/10.1016/j.jep.2014.09.049
- Huang, X., Liu, G., Guo, J., Su, Z. (2015). The PI3K/Akt pathway mediates the anti-apoptotic effect of berberine in the rat remnant kidney model. International Journal of Molecular Sciences, 16(2), 3092-3105. doi: 10.3390/ijms16023092
- Wang Y, Huang Y, Lam KS. Berberine and its derivatives: a patent review (2009–2012). Expert Opin Ther Pat. 2012;22(8):969-984.
- Gerard J, Soriano García J, Romo-Mancillas A, González-Cortazar M, Guzmán-Grenfell AM, Sánchez-Sevilla L. Effect of Berberine on Inflammatory and Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Antioxidants (Basel). 2021;10(2):282. doi: 10.3390/antiox10020282. PMID: 33673056; PMCID: PMC7914246.
Inhalt: 120 Kapseln Artikelnr.: 6792