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Glutamine Polyhydrate - GN Laboratories

15,50 €

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/ Content: 300g
0.4 kg
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  • Content: 300g
  • Form : Powder

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GN Glutamine Polyhydrate pH-buffered and probiotically enhanced for an increased molecular stability and unrivalled bioavailability!

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Available Now!

15,50 €

51,68 € per Kilo
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0.4 kg
Lieferzeit 1-2 Werktage
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Glutamine Polyhydrate

GN Glutamine Polyhydrate pH-buffered and probiotically enhanced for an increased molecular stability and unrivalled bioavailability


Product Highlights


  • highest molecular stability in the digestive tract due to an innovative buffering system
  • superior bioavailability
  • rapid and complete absorption
  • improved immune function
  • accelerated recovery after your workouts
  • unmatched anti-catabolic effects
  • up to +400% increase in growth hormone release when taken on an empty stomach
  • increased glycogen resynthesis
  • additional +20% increase in bioavailability due to the added probiotic bacteria
  • superior results at lower dosages compared to regular glutamine


Why makes Glutamine Polyhydrate so superior to every other form of glutamine?

Glutamine is one of the most popular dietary supplements among athletes and boydbuilders. Especially experienced athletes value its beneficial effects on the immune system and its ability to speed up post-workout recovery. Unfortunately, glutamine is not very stable once it’s dissolved in water. Few people are aware of the fact that it will decompose to urea and pyroglutamate even at a neutral pH. This also explains why most companies recommend ingesting their cheap glutamine powders immediately after dissolving them in a liquid of your choice.

Even if you adhere to these recommendations, the highly acidic milieu of the stomach will very likely degrade huge amounts of regular glutamine before it can be taken up by the epithelial cells in your gut. In the end, you will thus end up ingesting nothing but useless ammonia and ineffective pyroglutamate. In other words: As long as you stick to regular glutamine, only a marginal fraction will even make it past the gut linking intact.

While most supplement producers have been aware of this problem for years the only solution the market has had to offer up to now are various types of glutamine peptides. These are in fact much more stable than regular glutamine, but the peptides (combinations of two or more amino acids) do have a substantial downside: They are way more expensive than regular glutamine and that despite the fact that most of them contain no more than 30% glutamine.
Here at GN Laboratories, we are always trying to come up with innovative solutions – specifically if the “state of the art” supplements are not producing the desired and by no means the promised results. Our goal was thus to develop a glutamine supplement that would have both, a very high glutamine content and superior stability within the environment of the low pH environment of the stomach. Only a product that fulfills these criteria will yield maximal bioavailability and maximal results… Welcome in the world of Glutamine Polyhydrate from GN laboratories, the innovative glutamine formula with the highest bioavailability of all currently available glutamine preparations!

You will probably ask yourself now, how we have managed to succeed, where others have failed so miserable!? The major breakthrough unquestionably is the unique combination acid buffer, which protects the ingested glutamine molecules from breakdown. In the end, this is yet only part of the success formula, which would not be complete without the added probiotics, which increase the bioavailability of Glutamine Polyhydrate by another 20%! It’s the synergy of these two innovations which makes Glutamine Polyhydrate the #1 most bioavailable glutamine preparation on the market – a product that will allow your body to use no less than 100% of the glutamine you ingest!

It should be obvious that the increased absorption and utilization will reduce the overall amount of glutamine you will have to take to achieve the desired results. So, instead of the regular 10-15 grams of glutamine you will have to take no more than 3 grams to elicit results that are way superior to what you would see with any other glutamine preparation on the market. This makes Glutamine Polyhydrate not simply way more cost effective, but also much more convenient than any other glutamine product on the market. Moreover, the low dosage requirement will allow you to escape all of the known gastro-intestinal side effects such as bloating, flatulence and diarrhea. Glutamine Polyhydrate is thus not just the most innovative, most effective and most economical glutamine preparation on the market, it is also the best tolerated formula your money can buy.


What is glutamine and how can athletes benefit from glutamine supplementation?

Glutamine is one of the so-called non-essential amino acids, which can be produced by your body from other amino acids. This does yet not mean that glutamine, which is the most abundant free form amino acid in your body, is not necessary for the optimal physiological function of your body. It constitutes 20% of the total plasma free amino acid pool and its concentration in skeletal muscle ranges from 50-60%. A “non-essential” amino acid that’s present at ultra-high levels almost everywhere in your body? At first this may sound awkward, if you do yet take into consideration that the immune and digestive system alone require copious amounts of the universal nitrogen donor and acknowledge its central role in protein metabolism, it is yet only logical that our bodies need to have significant amounts of this non-essential yet vitally important amino acid available.

Since it can be synthesized from other amino acids, it would seem that it is very unlikely that we would ever be short of glutamine. There are however situations, in which our endogenous glutamine production does not suffice to meet the increased physiological requirements. Among the factors that increase the demand for glutamine are stress, sickness and – obviously – intense workouts (11). Scientific studies have conclusively shown that the glutamine pool can be lowered by up to 50% after only one intense workout. And these changes are not transient and short lived: It can take several hours until the glutamine pool is eventually repleted (8). Therefore, glutamine is often also referred to as a “conditionally essential amino acid”. This means that under certain circumstances our bodies’ own glutamine production does not meet the increased glutamine demands of our bodies.

It goes without saying that it is in these situations, when the endogenous glutamine production does not suffice to meet the contemporary demands, when the ingestion of supplemental glutamine is most beneficial, if not simply necessary. After all, our bodies need glutamine to keep some of the most fundamental bodily functions working. And to ensure that, it will willingly sacrifice lean muscle tissue in order to get access to its glutamine content and other amino acids which will subsequently be (ab-)used to produce glutamine (9). Even a short-lived glutamine shortage is thus the nightmare of every aspiring bodybuilder, because it will trigger rapid and profound skeletal muscle catabolism.
Fortunately, scientific studies have shown that the ingestion of glutamine supplements cannot just stop this highly undesirable lean mass loss in its tracks, but also increase the general efficacy of the protein synthetic cascade. In that, the combination of glutamine and glucose appears to offer an additional bonus, as previous studies have shown that co-administration of both can increase the plasma glutamine levels by up to 200% (4).

It’s thus up to you to decide whether you want to risk falling into the deep catabolic hole that opens when your glutamine stores have been drained during an intense workout or whether you rather pick up a bottle of Glutamine Polyhydrate to make sure that you start building muscle from the very moment you’re leaving the gym.


Are there other advantages that make supplementing with glutamine worthwhile?


Glutamine and the immune system

The rapidly proliferating cells of the immune system are heavily reliant on the presence of adequate amounts of glutamine. A lack – no matter how small – of this important amino acid results in reduced numbers of protective T-cells and will thus compromise your body’s ability to ward off bacterial and viral introducers (12). In short, even a relatively modest and transient glutamine deficiency can compromise your immune system in a way that will make you highly susceptible to infectious diseases. It is after all no coincidence that hard training athletes are particularly prone to infections (10). There is however plenty of scientific evidence that the provision of supplemental glutamine after intense athletic activity can protect and strengthen the immune system and thus reduce the susceptibility to infections significantly (1, 2). Other studies have been able to show that even non-athletes can benefit from the immune-supportive effects of glutamine. The latter is obviously of greatest interest during the winter months, when the risk of catching a cold is particularly high.

In the end, it does not really matter, though, whether you are a professional or recreational athlete. You certainly don’t want to risk that infectious diseases compromise the success of your training!? It would therefore be only logical to consider taking a serving of Glutamine Polyhydrate after each and every workout. This will help you to re-establish your compromised immune system before any of the opportunistic pathogens can take a hold of you.


Glutamine and growth hormone release

In a well-controlled study, scientists have been able to show that the administration of only 2 grams of glutamine can increase your body’s growth hormone (GH) production by up to 400% (3). As an athlete you will probably be aware that GH can stimulate protein synthesis and thus increase skeletal muscle growth. Growth hormone does also exert very pronounced lipolytic effects. Figuratively speaking, it squeezes the fat out of your adipose tissue, and promotes its subsequent oxidation in the mitochondria, the cellular power plants of your body.

If you want to supercharge your lean mass gains and simultaneously burn body fat, it would be advisable to consume two additional* of Glutamine Polyhydrate to your supplement regimen servings (*in addition to the one you take right after your workouts). One in the evening, right before you go to bed and the other one in the morning, immediately after you wake up. Both servings should be taken on an empty stomach to maximize the growth hormone response.


Glutamine and cell volume and skeletal muscle hypertrophy

Similar to creatine, glutamine has the ability to draw water into the muscle cells and thus increase the cell volume (6). The increase in cell volume will obviously give the muscles a fuller look. What most trainees are not aware of, though, is that the benefits of an increased cell volume are not of mere cosmetic nature. It will also help to establish an overall more anabolic milieu with all its beneficial downstream effects on protein and glycogen synthesis and the ensuing accrual of lean muscle mass (6).

In this respect, glutamine and creatine work synergistically. The same is obviously true for Glutamine and Creatine Polyhdrate, the two most potent glutamine and creatine formulas on the market. When taking just one of the two will already make you feel pumped, you can be certain that the combination of both of them will make you feel super swole.
In addition to the anabolic downstream effects of the increased cell volume, any increase in the glutamine content of the musculature exerts independent direct effects on the protein synthetic machinery in your muscles and will thus eventually improve skeletal muscle growth (7). It is therefore obvious that the anabolic effects of glutamine extend way beyond exercise recovery and growth hormone release. Glutamine and exercise recovery

It has already been mentioned several times: The provision of adequate amounts of intact, bioavailable glutamine right after a workout will prevent skeletal muscle catabolism and maximize the anabolic response to a given training stimulus. Several peer-reviewed studies have been able to show that glutamine can also promote the repletion of the intra-muscular glycogen stores after intense anaerobic workouts (4, 5). All this will allow your body to start building muscle at the very moment you leave the workout area. You will recover faster and be able to train at a higher frequency. Glutamine Polyhydrate can thus help you to set more frequent growth stimuli without running the risk of overtraining. The net result should be obvious: More growth stimuli + increased recovery = greater muscle gains!


Why are there additional probiotic bacteria in Glutamine Polyhydrate?

Here at GN Laboratories we are always trying to keep one step ahead of the competition as far as the practical realization of the latest scientific results are concerned. Therefore we did content ourselves with the addition of the innovative buffering system to Glutamine Polyhydrate. What’s the use of having a more stable molecule if it’s still not optimally observed? This is where the micro-encapsulated probiotics come in – Bifidobacterium Bifidum, Lactobacillus Acidophilus and Lactobacillus Casai which are all part of the unique pH buffered and probiotically enhanced formula of Glutamine Polyhydrate.

As the most recent scientific evidence suggests, these probiotics can increase the absorption and bioavailability of amino acids from the digestive tract by 20%. It is therefore probably not an overstatement, when we say that Glutamine Polyhydrate is the most bioavailable glutamine formula on the market.

The increase in bioavailability is yet only one of the beneficial effects the addition of the probiotic bacteria will have. Probiotics, especially those belonging to the Lactobacilli strains Lactobacillus Acidophilus und Lactobacillus Casai, which are both part of the Glutamine Polyhydrate formula, will help acidify the small intestine and thus protect you from the permanent assault of pathogens that reaches the upper part of your digestive tract with the foods you consume. The Bifidobacterium Bifidum bacteria, on the other hand, protect the large intestine from the invasion of pathogenic bacteria and fungal infections. The metabolic byproducts of the bacteria from the Bifido strain will also provide a readily available energy source for the cells of the intestinal wall. Without these bacteria the so-called colonocytes would be attacked by other bacteria from the gut flora and die.

The ill health effects this would entail range from mild digestive problems to chronic diseases of the digestive tract, such as Morbus Crohn. In addition, the bacteria themselves and their metabolic byproducts have been shown to strengthen the immune system. Against that background, it is no wonder that having low amounts of these beneficial gut inhabitants has been associated with weak immune defenses and an increased susceptibility to all kinds of infectious diseases.

Unfortunately, probiotics are living organisms that are easily destroyed by all sorts of environmental influences. To ensure that all the bacteria reach their destinations in your small and large intestine intact, we use only microencapsulated probiotics in Glutamine Polyhydrate and all our other probiotically enhanced products. The encapsulation protects the bacteria from harm and ensures that they can do their job right where they’re supposed to be: within your intestine!


The GN Laboratories quality guarantee

As with all our products, Glutamine Polyhydrate contains only the highest quality ingredients the supplement market has to offer. And to make sure that each and every bottle of your favorite GN Laboratory products is of the same top-notch quality, our company laboratory conducts regular tests on each and every product that leaves our facilities to make sure that the quality and purity of its ingredients match our ambitious standards.




  1. Castel LM, Newsholme EA. Glutamine and the effects of exhaustive exercise upon the immune response. Can J Physiol Pharmacol (1998). 76:524-536.
  2. Castel LM, Poortmans JR, Newsholme EA. Does glutamine have a role in reducing infections in athletes? Eur J Appl Physiol. 73:488-490.
  3. Wellbourne TC. Increased plasma bicarbonate and growth hormone after an oral glutamine load. Am J Clin Nutr (1995). 61:1058-1061.
  4. Van Hall, Saris WH, van de Schoor PH, Wagenmakers AJ. The effect of free glutamine and peptide ingestion in the rate of muscle glycogen resynthesis in man. Int J Sports Med 2000. 21 (1):25-30.
  5. Varnier M, Leese GP, Thompson J, Rennie MJ.Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am J Physiol (1995). 269 (2 Pt 1): E309-315.
  6. Haussinger D et al. Cellular hydration state: An important determinant of protein catabolism in health and disease. Lancet 341:1330-1332.1993.
  7. VanAcker BA,.et al. (1999) Glutamine:the pivot of our nitrogen economy? JPEN, 23:S45-8.
  8. Rowbottom DG, Keast D, Morton AR. The emerging role of glutamine as an indicator of exercise stress and overtraining. Sports Med. 1996 Feb;21(2):80-97. Review.
  9. Holecek M. Relation between glutamine, branched-chain amino acids, and protein metabolism. Nutrition. 2002 Feb;18(2):130-3. Review.
  10. Roth E, et al. (1982). Metabolic disorders in severe abdominal sepsis, glutamine deficiency in skeletal muscle. Clinical Nutrition 1. 25-41.
  11. Miller, A.L. (1999). Therapeutic considerations of l-glutamine. Alternative Medicine Review. 4: 239-48.
  12. Hack, V., Weiss, C., Friedmann, B., Suttner, S., Schykowski, M., Erge, N., Benner, A., Bartsch, P., and Droge, W. (1997). Decreased Plasma glutamine level and CD4+ T-cell number in response to 8 weeks of anaerobic training. American Journal of Physiology. 272: 788-95


  • Titel:ein muss
    Glutamin ist ein MUSS für jeden der Sport treibt. Es hilft bei der Regeneration und stärkt das Immunsystem. Ich nehme es morgens nach dem Aufstehen, während des Trainings und danach. Wirkung ist sehr sehr gut!
  • Titel:Top Glutamin
    Ich nehme täglich eine Portion vor dem Schlafen. An Trainingstagen eine weitere Portion direkt nach dem Workout. Dieses Glutamin hat einen deutlichen Effekt auf das Immunsystem. Ohne dieses Produkt wurde ich viel schneller erkältet. Jetzt seit Wochen gar nicht mehr.
  • Titel:Wirklich zu empfehlen!
    Ich nutze es neuderings vor und nach dem Training und muss eine gehörige Leistungssteigerung feststellen. Es wirkt verdammt schnell.
  • Titel:Mit ABSTAND das beste

    Das mit ABSTAND beste Glutamin, was ich jemals ausprobiert habe! Wirkt sofort und effektiv bei einer kleineren Dosierung als gewöhnliches Glutamin.
  • Titel:Mit ABSTAND das beste
    Mit das beste Glutamin was ich je probiert habe!! Wirkt sehr schnell, anabol, antikatabol, fettverbrennend und immunstabilisierend
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Directions for GN Glutamine Polyhydrate

Take one serving (3g) before, and one serving after your workout.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. KEEP OUT OF REACH OF CHILDREN.

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