Citrulline is considered as one of the most effective - if not the most effective - legally available nitric oxide booster you'll find on the market. Even though citrulline will increase your nitric oxide production using the same pathway as arginine, citrulline is much more effective than arginine in this regard. A great part of orally administered arginine will be broken down by your liver before it can do anything in your body, but citrulline will enter your bloodstream in maximum amounts and will be converted to arginine by your kidneys to maximize your nitric oxide production (3).
A maximum nitric oxide production will result in a maximum dilation of your blood vessels, to maximize the supply of blood to your hard-working muscles. This will not only cause a murderous, skin-bursting pump that will surpass anything you've ever experienced, but will also provide your hungry, hard-working muscles with maximum amounts of oxygen, essential nutrients, and endogenous anabolic hormones.
More oxygen and more nutrients will increase your muscle performance during brutal workouts to allow you to force those last, all-important repetitions that will make the difference between moderate and incredible gains of strength and muscle mass. Apart from this it will speed up your recovery between your insanely brutal sets and your grueling workouts.
This will allow you more brutal sets per workout and more frequent high intensive workouts without burning out, to leave your body no other choice than to respond with maximum gains of mass and strength!
Citrulline can delay muscle fatigue and muscle failure by using several other pathways apart from an increased supply of your muscles with oxygen and nutrients. These include an increased ATP production during exercise, to give you more energy for anaerobic weight training sessions as well as aerobic endurance training sessions.
In addition to this, citrulline is the limiting factor for the capacity of your body to break down ammonia, which is produced as a waste product of your energy metabolism during exercise (1). An accumulation of ammonia contributes to an acidification of your muscles and will speed up the onset of muscle failure. Therefore more citrulline means less ammonia and a later onset of muscle failure! And it gets even better: Citrulline will boost your muscle protein synthesis, helping you to gain rock-solid, lean muscle mass faster, while reducing your soreness after exercise and significantly increasing the number of executable repetitions (2).
1. Wilkerson JE, Batterton DL, Horvath SM. Exercise-induced changes in blood ammonia levels in humans. Eur J Appl Physiol Occup Physiol. 1977 Dec 22;37(4):255-63.
2. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010 May;24(5):1215-22.
3. Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, Spickler W, Schulze F, Böger RH. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2008 Jan;65(1):51-9.
Dissolve 5g powder in 200 to 300ml water and drink it.